Federal State Budgetary Educational Institution of Higher Education “Russian Biotechnology University (Rosbiotech)” (Department of Endocrinology, Medical Institute of Continuing Education, Head of Department)
Federal State Budgetary Educational Institution of Additional Professional Education "Russian Medical Academy of Continuous Professional Education" (Department of General Medical Practice and Outpatient Therapy, Associate Professor)
Russian Federation
Moskva, Moscow, Russian Federation
Russian Federation
Russian Federation
Recent researches have revealed strong interdependence between congestive heart failure, renal failure and anemia. Heart and kidney diseases have the same traditional risk factors including diabetes mellitus. Disorders of carbohydrate metabolism have a significant effect on the development of cardiorenal anemic syndrome components. On the other hand, the anemic syndrome in patients with diabetes mellitus is considered as a multifactorial process with a pronounced negative effect on the progression of chronic kidney disease and coronary vascular diseases worsening their course and prognosis
cardiorenal anemic syndrome, diabetes mellitus, anemia, complications, congestive heart failure, chronic kidney disease
1. World Heart Report 2023: Confronting the World’s Number One Killer. Geneva, Switzerland. World Heart Federation. – 2023.
2. The cardio renal anemia syndrome: correcting anemia in patients with resistant congestive heart failure can improve both cardiac and renal functional and reduce hospitalizations / D. Silverberg, D.Wexler, M. Blum, A. Iaina // Clinical nephrology. – 2003. – Vol. 60. – Suppl. – 1. – P. 93–102.
3. Kazmi W., Kausz A., Khan S. et al. Anemia: an early complication of chronic renal insufficiency. Am. J. Kidney Dis. – 2001; 38: 803–812.
4. Romanenko N.A., Bessmel'cev S.S., Rozanova O.E., Karpova, N.S., Abdulkadyrov K.M. Vliyanie urovnya FNO-α na effektivnost' korrekcii anemii u bol'nyh limfoproliferativnymi zabolevaniyami // Onkogematologiya. – 2010;(3):22–28.
5. Levin A. Left ventricular mass index increase in early renal disease: impact of decline in hemoglobin / A. Levin, C.R. Thompson, J. Ethier [et al.] // Am. J. Kidney. Dis. – 1999. – Vol. 34. – R. 125–134.
6. Vaziri N.D. Erytropoetin and transferrin metabolism in nephrotic syndrome // Am. J. Kidney Dis. – 2001; 38: 1–8.
7. McClellan W., Flanders W.D., Langston R.D. et al. Anemia and renal insufficiency are independent risk factors for death among patients with congestive heart failure admitted to community hospitals: a population-basedstudy // J. Am. Soc. Nephrol. – 2002; 13: 1928–1936.
8. Anker S.D., Sharma R. The syndrome of cardiac cachexia // Int. J. Cardiol. – 2002; 85: 51–66.
9. Anand I., McMurray J.J.V., Whitmore J. et al. Anemia and its relationship to clinical outcome in heart failure // Circulation. – 2004; 110: 149-154.
10. Tkachenko E.I., Borovkova N.Yu., Buyanova M.V. Anemiya pri hronicheskoy serdechnoy nedostatochnosti: vzglyad na patogenez i puti korrekcii // Doktor.Ru. – 2019. – № 2 (157) . – S. 31–36.
11. Abramov D., Cohen R.S., Katz S.D., Mancini D., Maurer M.S. Comparison of blood volume characteristics in anemic patients with low versus preserved left ventricular ejection fraction // Am J Cardiol. – 2008; 102: 1069–1072.
12. Andreichev L.A., Baleeva L.V. Anemiya hronicheskih zabolevaniy // Rus. med. zhurn. – 2014; 2: 50–5.
13. Symeonidis A., Kouraklis-Symeonidis A., Psiroyiannis A., et al. Inappropriately low erythropoietin response for the degree of anemia in patients with noninsulin – dependent diabetes mellitus // Ann. Hematol. – 2006. – Vol. 85. – № 2. – P. 79–85.
14. Shestakova M.V., Martynov S.A., Il'in A.V. i dr. Anemiya pri diabeticheskoy nefropatii: rasprostranennost', klinicheskie i patofiziologicheskie aspekty // Terapevticheskiy arhiv. – 2008. – № 6. – S. 41–47.
15. Thomas M.C. Epidemiology of hemoglobin levels in patients with type 2 diabetes / M.C. Thomas, C. Tsalamandris, R.J. MacIsaac, G. Jerums // American Journal of Kidney Diseases. – 2006. – Vol. 48. – P. 537–545.
16. Mrozikiewicz-Rakowska B., Chylińska A., Sieńko D. Vitamin B 12 in diabetes – a new treatment paradigm? // Clin. Diabetol. – 2020. – Vol. 9. – № 6. – P. 489–496.
17. Bareford D., Jennings P.E., Stone P.C., Baar S., Barnett A.H., Stuart J. Effects of hyperglycaemia and sorbitol accumulation on erythrocyte deformability in diabetes mellitus // J Clin Pathol. – 1986 Jul; 39(7):722–7.
18. Donnelly L.A., Dennis J.M., Coleman R.L., Sattar N., Hattersley A.T., Holman R.R., Pearson E.R. Risk of Anemia With Metformin Use in Type 2 Diabetes: A MASTERMIND Study // Diabetes Care. – 2020 Oct; 43(10):2493–2499.
19. Kaiser A.B., Zhang N., Pluijm W.V.D. Global prevalence of type 2 diabetes over the next ten years (2018–2028) // Diabetes. – 2018. – Vol. 67, suppl. 1.
20. Komajda M., Anker S.D., Charlesworth A. et al. for the COMET Investigators. The impact of new onset anaemia on morbidity and mortality in chronic heart failure: results from COMET // Eur Heart J. – 2006; 27(12):1440-6.
21. Holland D.C., Lam M. Predictors of hospitalization and death among pre-dialysis patients: a retrospective cohort study. Nephrol Dial Transplant. – 2000 May; 15(5):650–8.30.
22. Mohort T.V. Anemiya i saharnyy diabet: sluchaynaya ili zakonomernaya svyaz'? // Medicinskie novosti. – 2001. – № 3. – S. 76–81.
23. Smaradottir M.I., Ritsinger V., Gyberg V. et al. Copeptin in patients with acute myocardial infarction and newly detected glucose abnormalities – A marker of increased stress susceptibility? A report from the Glucose in Acute Myocardial Infarction cohort. Diab Vasc Dis Res. – 2017; 14 (2):69–76.
