Russian Federation
Russian Federation
Russian Federation
Moscow, Moscow, Russian Federation
The article is dedicated to the study of DEFB1, IL6 and IL17F genes’ expressive profile in the peripheral blood of the patients with primary open-angle glaucoma.
primary open-angle glaucoma, gene expression, DEFB1, IL6, IL17F, innate immunity, stages of the diseases
1. Abubakar S.A., Isa M.M., Omar N., Tan S.W. Relative quantification of human β‑defensins gene expression in pterygium and normal conjunctiva samples // Molecular Medicine Reports 22.6. – 2020: 4931–4937.
2. Ivanoshchuk D.E. et al. Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations // Vavilovskii zhurnal genetiki i selektsii. – 2020 – V. 24, 8: 861–867.
3. Nagstrup A.H. The use of benzalkonium chloride in topical glaucoma treatment: An investigation of the efficacy and safety of benzalkonium chloride-preserved intraocular pressure-lowering eye drops and their effect on conjunctival goblet cells // Acta ophthalmologica. – 2023 – V. 101 – Suppl 278: 3–21.
4. Zhai Yu-Jia et al. Defensins: defenders of human reproductive health // Human reproduction update. – 2023
5. Karadag R. et al. An investigation of human beta-defensins and cathelicidin expression in patients with pterygium // Arquivos brasileiros de oftalmologia. – 2017
6. Peng J. et al. A Review of the Tear Film Biomarkers Used to Diagnose Sjogren's Syndrome // International journal of molecular sciences. – 2024 Sep.
7. Soon M.Y. et al. Cytokine Expression in Staphylococcal and Streptococcal Endophthalmitis // Biomedicine hub. – 2022 Jul.
8. Yin L. et al. The expression of miRNA-146a-5p and its mechanism of treating dry eye syndrome // Journal of clinical laboratory analysis. – 2021
9. Yu-Wai-Man C. et al. Genotype-Phenotype Associations of IL6 and PRG4 With Conjunctival Fibrosis After Glaucoma Surgery // JAMA ophthalmology. – 2017
10. Samelska K. et al. Immunological and molecular basics of the primary open angle glaucoma pathomechanism // Central-European journal of immunology. – 2021
11. Garbutcheon-Singh K.B., Carnt N., Pattamatta U., Samarawickrama C., White A., Calder V. A Review of the Cytokine IL-17 in Ocular Surface and Corneal Disease // Curr Eye Res. – 2019 Jan; 44(1):1–10.
12. Gunadi A.V.C., Utami F.D.T. et al. Aberrant SOX10 and RET expressions in patients with Hirschsprung disease // BMC Pediatr. – 2024; 24(1):189.
