Russian Federation
Russian Federation
Russian Federation
Many researchers note growth of the share of systemic vasculitis in the structure of rheumatological diseases. One of such diseases is granulomatosis with polyangiitis. It is characterized by a variety of clinical manifestations which can make it difficult to obtain differential diagnosis. In this article the authors present a case of refractory course of the necrotizing scleritis in a patient with granulomatosis and polyangiitis.
granulomatosis with polyangiitis, antineutrophil cytoplasmic antibodies (ANCA), ANCA-associated vasculitis, necrotizing scleritis, refractory course
1. Haynes B.F., Fishman M.L., Fauci A.S. et al. The ocular manifestations of Wegener’s granulomatosis. Fifteen years experience and review of the literature // Am J Med. – 1977; 63(1):131- 41. Doi:https://doi.org/10.1016/0002-9343(77)90125-5
2. Mei L., Wang L., Yan H. Updates of ocular involvement in granulomatosis with polyangiitis // Graefes Arch Clin Exp Ophthalmol. – 2023; 261(6):1515–1523. Doi:https://doi.org/10.1007/s00417-022-05918-w
3. Mohammad A.J., Jacobsson L.T., Westman K.W. et al. Incidence and survival rates in Wegener’s granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and polyarteritis nodosa // Rheumatology (Oxford). – 2009; 48(12):1560–1565. Doi:https://doi.org/10.1093/rheumatology/kep304 4. Nakamura Y., Okumura F., Nihei M. et al. Granulomatosis with Polyangiitis following COVID-19 in an Adolescent // Intern Med. – 2023; 62(4):589–593. Doi:https://doi.org/10.2169/internalmedicine.1109-22
4. Selvaraj V., Moustafa A., Dapaah-Afriyie K. et al. COVID-19-induced granulomatosis with polyangiitis // BMJ Case Rep. – 2021; 14(3): e242142. Doi:https://doi.org/10.1136/bcr-2021-242142
5. Lee A.F., Wu J.S., Huang D.F. et al. Choroidal involvement in Wegener’s granulomatosis: a case report. Zhonghua Yi Xue Za Zhi (Taipei). – 1998; 61(8):496–499.
6. Izmaylova D.S., Novikov P.I., Grusha Yu.O. i dr. Chastota oftal'mologicheskih proyavleniy granulematoza s poliangiitom (Vegenera) i ih svyaz' s sistemnoy patologiey // Terapevticheskiy arhiv. – 2017; 89(5):69–73 Doi:https://doi.org/10.17116/terarkh201789569-73
7. Izmaylova D.S., Abramova Yu.V., Novikov P.I. i dr. Klinicheskie osobennosti razlichnyh proyavleniy granulematoza s poliangiitom // Arhiv klinicheskoy i eksperimental'noy oftal'mologii. – 2018; 256(9): 1751–1756. Doi:https://doi.org/10.1007/s00417-018-4014-9
8. Grusha Yu.O., Izmaylova D.S., Novikov P.I. i dr. Oftal'mologicheskie proyavleniya granulematoza s poliangiitom (granulematoza Vegenera) // Terapevticheskiy arhiv. – 2015; 87(12): 111–116. Doi:https://doi.org/10.17116/terarkh20158712111-116 Ris. 2. Obshirnyy yazvennyy defekt s yavleniyami kraevogo keratita pacienta P.: v verhney chasti defekta vidna prolabiruyuschaya cherez skleru sosudistaya obolochka. Sostoyanie – posle neodnokratnoy plastiki sklery i retroskleroplombirovaniya.
